摘要: 目的： 探讨儿童系统性红斑狼疮 (SLE) 与甲状腺功能异常的关系。方法：总结 1 例以甲状腺亢进为首发表现的系统性红斑狼疮患儿的临床资料，并复习相关文献。结果： 9 岁男孩，在诊断 “ 甲状腺功能亢进 ” 1 年后因出现皮疹伴血尿蛋白尿在我科经自身抗体、补体及肾活检病理学等检查明确诊断为 SLE 。结论：自身免疫性甲状腺疾病的患儿应早期进行 SLE 相关检查；已确诊 SLE 的患儿也需常规检测甲状腺功能，及时诊断并积极治疗 。

Abstract:   Object: To investigate the association of systemic lupus erythematosus (SLE) and dysthyreosis. Methods: In the present report, we described a SLE child who primary performanced hyperthyroidism, and retrospectively analyzed the relevant literature. Results: A 9-year-old boy with a history of hyperthyroidism over a period of one year, currently appearance rash, hematuria and proteinuria, and was diagnosed as SLE due to the results of antibody, complements, renal biopsy and other tests. Conclusion: Our experience suggests that dysthyreosis children should be early examined for symptoms and serology of SLE; and thyroid function tests should be regularly performed in SLE children for timely diagnosis and active treatment.